6WYI

Crystal structure of EchA19, enoyl-CoA hydratase from Mycobacterium tuberculosis

Summary for 6WYI

Entry DOI	10.2210/pdb6wyi/pdb
Descriptor	EchA19, enoyl-CoA hydratase, MAGNESIUM ION (3 entities in total)
Functional Keywords	mycobacterium tuberculosis, cholesterol metabolism, enoyl-coa hydratase, lyase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	30578.35
Authors	Bonds, A.C.,Garcia-Diaz, M.,Sampson, N.S. (deposition date: 2020-05-13, release date: 2020-07-29, Last modification date: 2023-10-18)
Primary citation	Bonds, A.C.,Yuan, T.,Werman, J.M.,Jang, J.,Lu, R.,Nesbitt, N.M.,Garcia-Diaz, M.,Sampson, N.S. Post-translational Succinylation ofMycobacterium tuberculosisEnoyl-CoA Hydratase EchA19 Slows Catalytic Hydration of Cholesterol Catabolite 3-Oxo-chol-4,22-diene-24-oyl-CoA. Acs Infect Dis., 6:2214-2224, 2020 Cited by PubMed: 32649175 DOI: 10.1021/acsinfecdis.0c00329 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.915 Å)

Structure validation