6WXQ

Crystal structure of CRISPR-associated transcription factor Csa3 complexed with cA4

Summary for 6WXQ

Entry DOI	10.2210/pdb6wxq/pdb
Descriptor	CRISPR-associated transcription factor Csa3 (Type I-A), cyclic tetraadenylate, GLYCEROL, ... (4 entities in total)
Functional Keywords	carf domain, whth, ring nuclease, second messenger, transcription
Biological source	Saccharolobus solfataricus More
Total number of polymer chains	3
Total formula weight	57937.96
Authors	Xia, P.,Dutta, A.,Parashar, V. (deposition date: 2020-05-11, release date: 2021-11-17, Last modification date: 2023-10-18)
Primary citation	Xia, P.,Dutta, A.,Gupta, K.,Batish, M.,Parashar, V. Structural basis of cyclic oligoadenylate binding to the transcription factor Csa3 outlines cross talk between type III and type I CRISPR systems. J.Biol.Chem., 298:101591-101591, 2022 Cited by PubMed: 35038453 DOI: 10.1016/j.jbc.2022.101591 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation