6WOR

Structure of the broadly neutralizing antibody HC1AM

Summary for 6WOR

Entry DOI	10.2210/pdb6wor/pdb
Descriptor	Fab HC1AM heavy chain, Fab HC1AM light chain (3 entities in total)
Functional Keywords	hcv, broadly neutralizing antibodies, bnabs, e2 core, ighv1-69, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	47776.70
Authors	Tzarum, N.,Wilson, I.A.,Law, M. (deposition date: 2020-04-25, release date: 2020-08-19, Last modification date: 2023-10-18)
Primary citation	Tzarum, N.,Giang, E.,Kadam, R.U.,Chen, F.,Nagy, K.,Augestad, E.H.,Velazquez-Moctezuma, R.,Keck, Z.Y.,Hua, Y.,Stanfield, R.L.,Dreux, M.,Prentoe, J.,Foung, S.K.H.,Bukh, J.,Wilson, I.A.,Law, M. An alternate conformation of HCV E2 neutralizing face as an additional vaccine target. Sci Adv, 6:eabb5642-eabb5642, 2020 Cited by PubMed: 32754640 DOI: 10.1126/sciadv.abb5642 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.601 Å)

Structure validation