6WOJ

Structure of the SARS-CoV-2 macrodomain (NSP3) in complex with ADP-ribose

Summary for 6WOJ

Entry DOI	10.2210/pdb6woj/pdb
Descriptor	Non-structural protein 3, ADENOSINE-5-DIPHOSPHORIBOSE (3 entities in total)
Functional Keywords	sars-cov-2, covid-19, macrodomain, adp-ribose binding, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains	4
Total formula weight	78215.97
Authors	Lovell, S.,Kashipathy, M.M.,Battaile, K.P.,Gao, F.P.,Fehr, A.R. (deposition date: 2020-04-24, release date: 2020-05-06, Last modification date: 2023-10-18)
Primary citation	Alhammad, Y.M.O.,Kashipathy, M.M.,Roy, A.,Gagne, J.P.,McDonald, P.,Gao, P.,Nonfoux, L.,Battaile, K.P.,Johnson, D.K.,Holmstrom, E.D.,Poirier, G.G.,Lovell, S.,Fehr, A.R. The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase. J.Virol., 95:-, 2021 Cited by PubMed: 33158944 DOI: 10.1128/JVI.01969-20 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation