6WL3

preTCRbeta-pMHC complex crystal structure

Summary for 6WL3

• Entry DOI: 10.2210/pdb6wl3/pdb
• Descriptor: H-2 class I histocompatibility antigen, K-B alpha chain, ARG-GLY-TYR-LEU-TYR-GLN-GLY-LEU, N15 preTCR beta (3 entities in total)
• Functional Keywords: pretcr, h-2kb, t cell development, beta selection, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 9
• Total formula weight: 149221.19

Authors

Li, X.,Mallis, R.J.,Mizsei, R.,Tan, K.,Reinherz, E.L.,Wang, J. (deposition date: 2020-04-18, release date: 2020-12-23, Last modification date: 2023-10-18)

• Primary citation: Li, X.,Mizsei, R.,Tan, K.,Mallis, R.J.,Duke-Cohan, J.S.,Akitsu, A.,Tetteh, P.W.,Dubey, A.,Hwang, W.,Wagner, G.,Lang, M.J.,Arthanari, H.,Wang, J.H.,Reinherz, E.L.; Pre-T cell receptors topologically sample self-ligands during thymocyte beta-selection.; Science, 371:181-185, 2021; PubMed: 33335016; DOI: 10.1126/science.abe0918

Experimental method

X-RAY DIFFRACTION (3.45 Å)