6WGJ
Fab portion of dupilumab with Crystal Kappa design and no interchain disulfide
Summary for 6WGJ
| Entry DOI | 10.2210/pdb6wgj/pdb |
| Descriptor | Dupilumab Fab heavy chain, Dupilumab Fab light chain (3 entities in total) |
| Functional Keywords | dupilumab, hil4r, immune system |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 8 |
| Total formula weight | 196018.07 |
| Authors | Druzina, Z.,Atwell, S.,Pustilnik, A.,Antonysamy, S.,Ho, C.,Lieu, R.,Hendle, J.,Benach, J.,Wang, J. (deposition date: 2020-04-05, release date: 2020-09-16, Last modification date: 2023-10-18) |
| Primary citation | Lieu, R.,Antonysamy, S.,Druzina, Z.,Ho, C.,Kang, N.R.,Pustilnik, A.,Wang, J.,Atwell, S. Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing. Plos One, 15:e0232311-e0232311, 2020 Cited by PubMed: 32915778DOI: 10.1371/journal.pone.0232311 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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