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6WG1

Crystal structure of Fab399 in complex with NPNA6 peptide from circumsporozoite protein

Summary for 6WG1
Entry DOI10.2210/pdb6wg1/pdb
DescriptorFab399 heavy chain, Fab399 light chain, NPNA6 peptide, ... (4 entities in total)
Functional Keywordsmalaria, sporozoite, circumsporozoite protein, antibody, immune system
Biological sourceHomo sapiens (Human)
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Total number of polymer chains5
Total formula weight98352.29
Authors
Pholcharee, T.,Oyen, D.,Wilson, I.A. (deposition date: 2020-04-04, release date: 2020-07-29, Last modification date: 2024-04-03)
Primary citationPholcharee, T.,Oyen, D.,Flores-Garcia, Y.,Gonzalez-Paez, G.,Han, Z.,Williams, K.L.,Volkmuth, W.,Emerling, D.,Locke, E.,Richter King, C.,Zavala, F.,Wilson, I.A.
Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12:1063-1063, 2021
Cited by
PubMed: 33594061
DOI: 10.1038/s41467-021-21221-4
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.086 Å)
Structure validation

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