6WEW
Crystal structures of human E-NPP 1: bound to N-{4-[(7-methoxyquinolin-4-yl)oxy]phenyl}sulfuric diamide
This is a non-PDB format compatible entry.
Summary for 6WEW
Entry DOI | 10.2210/pdb6wew/pdb |
Descriptor | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, 1,2-ETHANEDIOL, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | human e-npp 1; drug discovery; inhibitors, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 215035.33 |
Authors | Peat, T.S.,Dennis, M.,Newman, J. (deposition date: 2020-04-03, release date: 2020-09-09, Last modification date: 2023-10-18) |
Primary citation | Dennis, M.L.,Newman, J.,Dolezal, O.,Hattarki, M.,Surjadi, R.N.,Nuttall, S.D.,Pham, T.,Nebl, T.,Camerino, M.,Khoo, P.S.,Monahan, B.J.,Peat, T.S. Crystal structures of human ENPP1 in apo and bound forms. Acta Crystallogr D Struct Biol, 76:889-898, 2020 Cited by PubMed: 32876064DOI: 10.1107/S2059798320010505 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.73 Å) |
Structure validation
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