6WEO

IL-22 Signaling Complex with IL-22R1 and IL-10Rbeta

Summary for 6WEO

• Entry DOI: 10.2210/pdb6weo/pdb
• Descriptor: Interleukin-10 receptor subunit beta, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-3)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (14 entities in total)
• Functional Keywords: interleukin, receptor, cytokine, signaling
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 36
• Total formula weight: 781898.09

Authors

Saxton, R.A.,Jude, K.M.,Henneberg, L.T.,Garcia, K.C. (deposition date: 2020-04-02, release date: 2021-04-28, Last modification date: 2023-10-18)

• Primary citation: Saxton, R.A.,Henneberg, L.T.,Calafiore, M.,Su, L.,Jude, K.M.,Hanash, A.M.,Garcia, K.C.; The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design.; Immunity, 54:660-672.e9, 2021; PubMed: 33852830; DOI: 10.1016/j.immuni.2021.03.008

Experimental method

X-RAY DIFFRACTION (2.6 Å)