6W2L

Crystal structure of human dehydrodolichyl diphosphate synthase (NgBR/DHDDS) in complex with Mg and IPP

Summary for 6W2L

Entry DOI	10.2210/pdb6w2l/pdb
Descriptor	Dehydrodolichyl diphosphate synthase complex subunit DHDDS, Dehydrodolichyl diphosphate synthase complex subunit NUS1, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	cis-prenyltransferase, dehydrodolichyl diphosphate synthase, transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	63058.15
Authors	Edani, B.H.,Ha, Y.,Sessa, W.C. (deposition date: 2020-03-06, release date: 2020-08-19, Last modification date: 2023-10-18)
Primary citation	Edani, B.H.,Grabinska, K.A.,Zhang, R.,Park, E.J.,Siciliano, B.,Surmacz, L.,Ha, Y.,Sessa, W.C. Structural elucidation of thecis-prenyltransferase NgBR/DHDDS complex reveals insights in regulation of protein glycosylation. Proc.Natl.Acad.Sci.USA, 117:20794-20802, 2020 Cited by PubMed: 32817466 DOI: 10.1073/pnas.2008381117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.306 Å)

Structure validation