6VYV
Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
Summary for 6VYV
Entry DOI | 10.2210/pdb6vyv/pdb |
EMDB information | 21473 |
Descriptor | E1 glycoprotein, E2 glycoprotein, Fab CHK-265 heavy chain, ... (4 entities in total) |
Functional Keywords | virus, monoclonal antibody, complex, viral protein-immune system complex, viral protein/immune system |
Biological source | Ross river virus (strain T48) (RRV) More |
Total number of polymer chains | 16 |
Total formula weight | 510368.87 |
Authors | Miller, A.S.,Kuhn, R.J. (deposition date: 2020-02-27, release date: 2020-08-26, Last modification date: 2024-03-06) |
Primary citation | Powell, L.A.,Miller, A.,Fox, J.M.,Kose, N.,Klose, T.,Kim, A.S.,Bombardi, R.,Tennekoon, R.N.,Dharshan de Silva, A.,Carnahan, R.H.,Diamond, M.S.,Rossmann, M.G.,Kuhn, R.J.,Crowe Jr., J.E. Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site. Cell Host Microbe, 28:699-711.e7, 2020 Cited by PubMed: 32783883DOI: 10.1016/j.chom.2020.07.008 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (6.33 Å) |
Structure validation
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