6VJS

Escherichia coli RNA polymerase and ureidothiophene-2-carboxylic acid complex

Summary for 6VJS

Entry DOI	10.2210/pdb6vjs/pdb
Descriptor	DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (8 entities in total)
Functional Keywords	rna polymerase transcription, transcription
Biological source	Escherichia coli More
Total number of polymer chains	12
Total formula weight	920596.41
Authors	Murakami, K.S.,Molodtsov, V. (deposition date: 2020-01-17, release date: 2020-10-07, Last modification date: 2023-10-11)
Primary citation	Haupenthal, J.,Kautz, Y.,Elgaher, W.A.M.,Patzold, L.,Rohrig, T.,Laschke, M.W.,Tschernig, T.,Hirsch, A.K.H.,Molodtsov, V.,Murakami, K.S.,Hartmann, R.W.,Bischoff, M. Evaluation of Bacterial RNA Polymerase Inhibitors in a Staphylococcus aureus -Based Wound Infection Model in SKH1 Mice. Acs Infect Dis., 6:2573-2581, 2020 Cited by PubMed: 32886885 DOI: 10.1021/acsinfecdis.0c00034 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.02 Å)

Structure validation