6VHE
FphF, Staphylococcus aureus fluorophosphonate-binding serine hydrolases F, KT130 bound
Summary for 6VHE
Entry DOI | 10.2210/pdb6vhe/pdb |
Descriptor | Esterase family protein, (2~{R})-2-phenylpiperidine-1-carbaldehyde (3 entities in total) |
Functional Keywords | fphf, fluorophosphonate-binding, serine hydrolases, sodium bound, acyl, kt130, intermediate, hydrolase |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 4 |
Total formula weight | 117580.30 |
Authors | Fellner, M.,Mace, P.D. (deposition date: 2020-01-09, release date: 2020-09-16, Last modification date: 2023-10-11) |
Primary citation | Fellner, M.,Lentz, C.S.,Jamieson, S.A.,Brewster, J.L.,Chen, L.,Bogyo, M.,Mace, P.D. Structural Basis for the Inhibitor and Substrate Specificity of the Unique Fph Serine Hydrolases of Staphylococcus aureus . Acs Infect Dis., 6:2771-2782, 2020 Cited by PubMed: 32865965DOI: 10.1021/acsinfecdis.0c00503 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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