6VC2

LRH-1 bound to SS-RJW100 and a fragment of the Tif2 Coactivator

Summary for 6VC2

Entry DOI	10.2210/pdb6vc2/pdb
Descriptor	Nuclear receptor subfamily 5 group A member 2, Nuclear receptor coactivator 2, (1S,3aS,6aS)-5-hexyl-4-phenyl-3a-(1-phenylethenyl)-1,2,3,3a,6,6a-hexahydropentalen-1-ol, ... (4 entities in total)
Functional Keywords	nuclear hormone receptor, transcription
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	30527.30
Authors	Mays, S.G.,Ortlund, E.A. (deposition date: 2019-12-20, release date: 2020-12-23, Last modification date: 2023-10-11)
Primary citation	Mays, S.G.,Stec, J.,Liu, X.,D'Agostino, E.H.,Whitby, R.J.,Ortlund, E.A. Enantiomer-specific activities of an LRH-1 and SF-1 dual agonist. Sci Rep, 10:22279-22279, 2020 Cited by PubMed: 33335203 DOI: 10.1038/s41598-020-79251-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.697 Å)

Structure validation