6VBG

Lactose permease complex with thiodigalactoside and nanobody 9043

Summary for 6VBG

Entry DOI	10.2210/pdb6vbg/pdb
Descriptor	Galactoside permease, nanobody 9043, beta-D-galactopyranose-(1-1)-1-thio-beta-D-galactopyranose, ... (5 entities in total)
Functional Keywords	major facilitator superfamily, symport, alternate access conformation change, nanobody binding, protein transport
Biological source	Escherichia coli More
Total number of polymer chains	4
Total formula weight	123956.51
Authors	Kumar, H.,Stroud, R.M.,Kaback, H.R.,Finer-Moore, J.,Smirnova, I.,Kasho, V.,Pardon, E.,Steyart, J. (deposition date: 2019-12-18, release date: 2020-11-25, Last modification date: 2023-10-11)
Primary citation	Kumar, H.,Finer-Moore, J.,Smirnova, I.,Kasho, V.,Pardon, E.,Steyaert, J.,Kaback, H.R.,Stroud, R.M. Diversity in kinetics correlated with structure in nano body-stabilized LacY. Plos One, 15:e0232846-e0232846, 2020 Cited by PubMed: 32380514 DOI: 10.1371/journal.pone.0232846 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation