6V7X

Structure of a phage-encoded quorum sensing anti-activator, Aqs1 bound to LasR

Summary for 6V7X

Entry DOI	10.2210/pdb6v7x/pdb
Descriptor	QUORUM SENSING ANTI-ACTIVATOR PROTEIN AQS1, Transcriptional regulator LasR, N-3-OXO-DODECANOYL-L-HOMOSERINE LACTONE, ... (4 entities in total)
Functional Keywords	prophage protein, viral protein, dna binding protein-viral protein complex, dna binding protein/viral protein
Biological source	Pseudomonas virus DMS3 More
Total number of polymer chains	3
Total formula weight	42243.74
Authors	Shah, M.,Moraes, T.F.,Maxwell, K.L. (deposition date: 2019-12-09, release date: 2020-12-16, Last modification date: 2023-10-11)
Primary citation	Shah, M.,Taylor, V.L.,Bona, D.,Tsao, Y.,Stanley, S.Y.,Pimentel-Elardo, S.M.,McCallum, M.,Bondy-Denomy, J.,Howell, P.L.,Nodwell, J.R.,Davidson, A.R.,Moraes, T.F.,Maxwell, K.L. A phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa. Mol.Cell, 81:571-583.e6, 2021 Cited by PubMed: 33412111 DOI: 10.1016/j.molcel.2020.12.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation