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6V7W

Crystal structure of LasR-Aqs1 complex from Pseudomonas aeruginosa

Summary for 6V7W
Entry DOI10.2210/pdb6v7w/pdb
DescriptorTranscriptional regulator LasR, QUORUM SENSING ANTI-ACTIVATOR PROTEIN AQS1, N-3-OXO-DODECANOYL-L-HOMOSERINE LACTONE, ... (4 entities in total)
Functional Keywordsprophage protein, quorum sensing, dna binding protein, dna binding protein-viral protein complex, dna binding protein/viral protein
Biological sourcePseudomonas aeruginosa (strain UCBPP-PA14)
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Total number of polymer chains6
Total formula weight84487.48
Authors
Shah, M.,Moraes, T.F.,Maxwell, K.L. (deposition date: 2019-12-09, release date: 2020-12-16, Last modification date: 2023-10-11)
Primary citationShah, M.,Taylor, V.L.,Bona, D.,Tsao, Y.,Stanley, S.Y.,Pimentel-Elardo, S.M.,McCallum, M.,Bondy-Denomy, J.,Howell, P.L.,Nodwell, J.R.,Davidson, A.R.,Moraes, T.F.,Maxwell, K.L.
A phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa.
Mol.Cell, 81:571-583.e6, 2021
Cited by
PubMed: 33412111
DOI: 10.1016/j.molcel.2020.12.011
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

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