6URX

Crystal structure of ricin A chain in complex with inhibitor 5-phenyl-2-thiophenecarboxylic acid

Summary for 6URX

• Entry DOI: 10.2210/pdb6urx/pdb
• Descriptor: Ricin, 1,2-ETHANEDIOL, 5-phenylthiophene-2-carboxylic acid, ... (5 entities in total)
• Functional Keywords: ricin a chain, rta, hydrolase, toxin, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Ricinus communis (Castor bean)
• Total number of polymer chains: 1
• Total formula weight: 31281.35

Authors

Harijan, R.K.,Li, X.P.,Bonanno, J.B.,Almo, S.C.,Tumer, N.E.,Schramm, V.L. (deposition date: 2019-10-24, release date: 2020-06-17, Last modification date: 2023-10-11)

• Primary citation: Li, X.P.,Harijan, R.K.,Kahn, J.N.,Schramm, V.L.,Tumer, N.E.; Small Molecule Inhibitors Targeting the Interaction of Ricin Toxin A Subunit with Ribosomes.; Acs Infect Dis., 6:1894-1905, 2020; PubMed: 32428396; DOI: 10.1021/acsinfecdis.0c00127

Experimental method

X-RAY DIFFRACTION (1.99 Å)