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6UO2

Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 1 (CD1) complexed with Trichostatin A

Summary for 6UO2
Entry DOI10.2210/pdb6uo2/pdb
DescriptorHDAC6, ZINC ION, POTASSIUM ION, ... (5 entities in total)
Functional Keywordshistone deacetylase, hydrolase
Biological sourceDanio rerio (Zebrafish)
Total number of polymer chains2
Total formula weight81481.13
Authors
Osko, J.D.,Christianson, D.W. (deposition date: 2019-10-14, release date: 2019-12-04, Last modification date: 2023-10-11)
Primary citationOsko, J.D.,Christianson, D.W.
Structural Basis of Catalysis and Inhibition of HDAC6 CD1, the Enigmatic Catalytic Domain of Histone Deacetylase 6.
Biochemistry, 58:4912-4924, 2019
Cited by
PubMed: 31755702
DOI: 10.1021/acs.biochem.9b00934
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.65002315533 Å)
Structure validation

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