6UMF
Crystal structure of human GAC in complex with inhibitor UPGL00012
Summary for 6UMF
Entry DOI | 10.2210/pdb6umf/pdb |
Descriptor | Glutaminase kidney isoform, mitochondrial, N-(5-{[1-(5-amino-1,3,4-thiadiazol-2-yl)piperidin-4-yl]oxy}-1,3,4-thiadiazol-2-yl)-2-phenylacetamide (3 entities in total) |
Functional Keywords | inhibitor, complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 232931.00 |
Authors | Huang, Q.,Cerione, R.A. (deposition date: 2019-10-09, release date: 2020-10-14, Last modification date: 2023-10-11) |
Primary citation | Huang, Q.,Cerione, R.A. Crystal structure of human GAC in complex with inhibitor UPGL00012 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.68 Å) |
Structure validation
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