6ULF

Crystal structure of 4498 Fab in complex with circumsporozoite protein NDN3 and anti-Kappa VHH domain

Summary for 6ULF

Entry DOI	10.2210/pdb6ulf/pdb
Descriptor	4498 Fab heavy chain, 4498 Fab light chain, anti Kappa VHH domain, ... (5 entities in total)
Functional Keywords	malaria, antibody, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	60684.07
Authors	Thai, E.,Scally, S.W.,Prieto, K.,Murugan, R.,Wardemann, H.,Julien, J.P. (deposition date: 2019-10-07, release date: 2020-06-17, Last modification date: 2023-10-11)
Primary citation	Murugan, R.,Scally, S.W.,Costa, G.,Mustafa, G.,Thai, E.,Decker, T.,Bosch, A.,Prieto, K.,Levashina, E.A.,Julien, J.P.,Wardemann, H. Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs. Nat. Med., 26:1135-1145, 2020 Cited by PubMed: 32451496 DOI: 10.1038/s41591-020-0881-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation