6UIQ

Crystal structure of wild-type human phosphoglucomutase 1 in complex with Glucose-6-Phosphate

Replaces:  6BJ0

Summary for 6UIQ

• Entry DOI: 10.2210/pdb6uiq/pdb
• Related: 5EPC
• Descriptor: phosphoglucomutase-1, 6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: phosphoglucomutase, g6p, isomerase
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 128952.35

Authors

Stiers, K.M.,Beamer, L.J. (deposition date: 2019-10-01, release date: 2020-08-12, Last modification date: 2023-10-11)

• Primary citation: Stiers, K.M.,Beamer, L.J.; A Hotspot for Disease-Associated Variants of Human PGM1 Is Associated with Impaired Ligand Binding and Loop Dynamics.; Structure, 26:1337-1345.e3, 2018; PubMed: 30122451; DOI: 10.1016/j.str.2018.07.005

Experimental method

X-RAY DIFFRACTION (2.3 Å)