6UHU
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 5-[(3-aminopropyl)amino]pentylboronic acid
Summary for 6UHU
Entry DOI | 10.2210/pdb6uhu/pdb |
Descriptor | Polyamine deacetylase HDAC10, 5-(3-azanylpropylamino)pentyl-$l^{3}-oxidanyl-bis(oxidanyl)boron, ZINC ION, ... (6 entities in total) |
Functional Keywords | histone deacetylase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Danio rerio |
Total number of polymer chains | 1 |
Total formula weight | 75675.21 |
Authors | Herbst-Gervasoni, C.J.,Christianson, D.W. (deposition date: 2019-09-28, release date: 2019-12-04, Last modification date: 2023-10-11) |
Primary citation | Herbst-Gervasoni, C.J.,Christianson, D.W. Binding ofN8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation. Biochemistry, 58:4957-4969, 2019 Cited by PubMed: 31746596DOI: 10.1021/acs.biochem.9b00906 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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