6UFN
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 7-[(3-aminopropyl)amino]heptan-2-one
Summary for 6UFN
| Entry DOI | 10.2210/pdb6ufn/pdb |
| Descriptor | Polyamine deacetylase HDAC10, 7-[(3-aminopropyl)amino]heptane-2,2-diol, ZINC ION, ... (6 entities in total) |
| Functional Keywords | histone deacetylase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Danio rerio (Zebrafish) |
| Total number of polymer chains | 1 |
| Total formula weight | 75769.41 |
| Authors | Herbst-Gervasoni, C.J.,Christianson, D.W. (deposition date: 2019-09-24, release date: 2019-12-04, Last modification date: 2023-10-11) |
| Primary citation | Herbst-Gervasoni, C.J.,Christianson, D.W. Binding ofN8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation. Biochemistry, 58:4957-4969, 2019 Cited by PubMed: 31746596DOI: 10.1021/acs.biochem.9b00906 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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