6U7A

Rv3722c in complex with kynurenine

Summary for 6U7A

• Entry DOI: 10.2210/pdb6u7a/pdb
• Descriptor: Aminotransferase, (2S)-4-(2-aminophenyl)-2-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-4-oxobutanoic acid, PHOSPHATE ION, ... (9 entities in total)
• Functional Keywords: aminotransferase, mycobacterium tuberculosis, transferase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 8
• Total formula weight: 384702.59

Authors

Mandyoli, L.,Sacchettini, J. (deposition date: 2019-09-01, release date: 2020-05-06, Last modification date: 2023-10-11)

• Primary citation: Jansen, R.S.,Mandyoli, L.,Hughes, R.,Wakabayashi, S.,Pinkham, J.T.,Selbach, B.,Guinn, K.M.,Rubin, E.J.,Sacchettini, J.C.,Rhee, K.Y.; Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis.; Nat Commun, 11:1960-1960, 2020; PubMed: 32327655; DOI: 10.1038/s41467-020-15876-8

Experimental method

X-RAY DIFFRACTION (2.22 Å)