6TZF

ADC-7 in complex with boronic acid transition state inhibitor S17079

Summary for 6TZF

Entry DOI	10.2210/pdb6tzf/pdb
Descriptor	Beta-lactamase, 3-(1-{[hydroxy(phosphonooxy)boranyl]methyl}-1H-1,2,3-triazol-4-yl)benzoic acid (3 entities in total)
Functional Keywords	inhibitor, beta-lactamase, batsi, adc-7, hydrolase
Biological source	Acinetobacter baumannii
Total number of polymer chains	4
Total formula weight	164541.96
Authors	Fish, E.R.,Powers, R.A.,Wallar, B.J. (deposition date: 2019-08-12, release date: 2020-06-24, Last modification date: 2023-10-11)
Primary citation	Caselli, E.,Fini, F.,Introvigne, M.L.,Stucchi, M.,Taracila, M.A.,Fish, E.R.,Smolen, K.A.,Rather, P.N.,Powers, R.A.,Wallar, B.J.,Bonomo, R.A.,Prati, F. 1,2,3-Triazolylmethaneboronate: A Structure Activity Relationship Study of a Class of beta-Lactamase Inhibitors againstAcinetobacter baumanniiCephalosporinase. Acs Infect Dis., 6:1965-1975, 2020 Cited by PubMed: 32502340 DOI: 10.1021/acsinfecdis.0c00254 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.96 Å)

Structure validation