6TVJ
Solution structure of PD-i3 peptide inhibitor of the human PD-1 extracellular domain
Summary for 6TVJ
| Entry DOI | 10.2210/pdb6tvj/pdb |
| Related | 6TT6 |
| NMR Information | BMRB: 34474 |
| Descriptor | PD-i3 peptide (1 entity in total) |
| Functional Keywords | immunotherapy, heterochiral peptide, computational design, de novo protein |
| Biological source | synthetic construct |
| Total number of polymer chains | 1 |
| Total formula weight | 1345.52 |
| Authors | Guardiola, S.,Varese, M.,Garcia, J.,Giralt, E. (deposition date: 2020-01-09, release date: 2021-01-27, Last modification date: 2023-06-14) |
| Primary citation | Guardiola, S.,Varese, M.,Roig, X.,Sanchez-Navarro, M.,Garcia, J.,Giralt, E. Target-templated de novo design of macrocyclic d-/l-peptides: discovery of drug-like inhibitors of PD-1. Chem Sci, 12:5164-5170, 2021 Cited by PubMed: 34163753DOI: 10.1039/d1sc01031j PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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