6TLU

HUMAN CK2 KINASE ALPHA SUBUNIT IN COMPLEX WITH THE ATP-COMPETITIVE INHIBITOR 4,5-DIBROMOBENZOTRIAZOLE

This is a non-PDB format compatible entry.

Summary for 6TLU

• Entry DOI: 10.2210/pdb6tlu/pdb
• Descriptor: Casein kinase II subunit alpha, 6,7-bis(bromanyl)-1~{H}-benzotriazole, SODIUM ION, ... (4 entities in total)
• Functional Keywords: ck2, casein kinase 2, inhibitor, bromo-benzotriazole, halogen bond, transferase-transferase inhibitor complex, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 46856.52

Authors

Czapinska, H.,Piasecka, A.,Winiewska-Szajewska, M.,Bochtler, M.,Poznanski, J. (deposition date: 2019-12-03, release date: 2020-12-16, Last modification date: 2024-01-24)

• Primary citation: Czapinska, H.,Winiewska-Szajewska, M.,Szymaniec-Rutkowska, A.,Piasecka, A.,Bochtler, M.,Poznanski, J.; Halogen Atoms in the Protein-Ligand System. Structural and Thermodynamic Studies of the Binding of Bromobenzotriazoles by the Catalytic Subunit of Human Protein Kinase CK2.; J.Phys.Chem.B, 125:2491-2503, 2021; PubMed: 33689348; DOI: 10.1021/acs.jpcb.0c10264

Experimental method

X-RAY DIFFRACTION (1.81 Å)