6THU

Crystal structure of the SVS_A2 protein (A224I mutant) from ancestral sequence reconstruction at 2.6 A resolution

Summary for 6THU

Entry DOI	10.2210/pdb6thu/pdb
Descriptor	SVS_AS10 variant (2 entities in total)
Functional Keywords	crystal structure of the design protein svs_as10 variant at 2.6 a resolution biosynthetic protein, biosynthetic protein
Biological source	Streptomyces sp. CWA1
Total number of polymer chains	2
Total formula weight	81035.73
Authors	Rudraraju, R.,Schnell, R.,Schneider, G. (deposition date: 2019-11-21, release date: 2020-12-02, Last modification date: 2024-01-24)
Primary citation	Schriever, K.,Saenz-Mendez, P.,Rudraraju, R.S.,Hendrikse, N.M.,Hudson, E.P.,Biundo, A.,Schnell, R.,Syren, P.O. Engineering of Ancestors as a Tool to Elucidate Structure, Mechanism, and Specificity of Extant Terpene Cyclase. J.Am.Chem.Soc., 143:3794-3807, 2021 Cited by PubMed: 33496585 DOI: 10.1021/jacs.0c10214 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation