6T70

Structure of the Bottromycin epimerase BotH in complex with Bottromycin A2 derivative

Summary for 6T70

• Entry DOI: 10.2210/pdb6t70/pdb
• Descriptor: BotH, CHLORIDE ION, GLYCEROL, ... (7 entities in total)
• Functional Keywords: bottromycin, ripp, epimerase, abh, hydrolase
• Biological source: Streptomyces sp. BC16019
• Total number of polymer chains: 1
• Total formula weight: 34342.13

Authors

Koehnke, J.,Sikandar, A. (deposition date: 2019-10-20, release date: 2020-07-15, Last modification date: 2024-01-24)

• Primary citation: Sikandar, A.,Franz, L.,Adam, S.,Santos-Aberturas, J.,Horbal, L.,Luzhetskyy, A.,Truman, A.W.,Kalinina, O.V.,Koehnke, J.; The bottromycin epimerase BotH defines a group of atypical alpha / beta-hydrolase-fold enzymes.; Nat.Chem.Biol., 16:1013-1018, 2020; PubMed: 32601484; DOI: 10.1038/s41589-020-0569-y

Experimental method

X-RAY DIFFRACTION (1.58 Å)