6T60

Crystal structure of Acinetobacter baumannii FabG at 1.66 A resolution

Summary for 6T60

Entry DOI	10.2210/pdb6t60/pdb
Descriptor	3-oxoacyl-(Acyl-carrier-protein) reductase (2 entities in total)
Functional Keywords	fatty acid biosynthesis, fabg, (3-oxoacyl-(acyl-carrier-protein) reductase), fas-ii, biosynthetic protein
Biological source	Acinetobacter baumannii
Total number of polymer chains	2
Total formula weight	52193.27
Authors	Vella, P.,Schnell, R.,Schneider, G. (deposition date: 2019-10-17, release date: 2020-11-18, Last modification date: 2024-01-24)
Primary citation	Vella, P.,Rudraraju, R.S.,Lundback, T.,Axelsson, H.,Almqvist, H.,Vallin, M.,Schneider, G.,Schnell, R. A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogens. Bioorg.Med.Chem., 30:115898-115898, 2020 Cited by PubMed: 33388594 DOI: 10.1016/j.bmc.2020.115898 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.66 Å)

Structure validation