6T58

Structure determination of the transactivation domain of p53 in complex with S100A4 using annexin A2 as a crystallization chaperone

Summary for 6T58

Entry DOI	10.2210/pdb6t58/pdb
Descriptor	Cellular tumor antigen p53,Protein S100-A4,Protein S100-A4,Annexin A2, GLYCEROL, CALCIUM ION (3 entities in total)
Functional Keywords	crystallization chaperon, peptide-protein complex, ca2+ binding, peptide binding protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	127375.09
Authors	Ecsedi, P.,Gogl, G.,Nyitray, L. (deposition date: 2019-10-15, release date: 2020-05-27, Last modification date: 2024-01-31)
Primary citation	Ecsedi, P.,Gogl, G.,Hof, H.,Kiss, B.,Harmat, V.,Nyitray, L. Structure Determination of the Transactivation Domain of p53 in Complex with S100A4 Using Annexin A2 as a Crystallization Chaperone. Structure, 28:943-953.e4, 2020 Cited by PubMed: 32442400 DOI: 10.1016/j.str.2020.05.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation