6T06

Crystal structure of YTHDC1 with fragment 19 (DHU_DC1_045)

Summary for 6T06

Entry DOI	10.2210/pdb6t06/pdb
Descriptor	YTHDC1, SULFATE ION, 3-imidazolidin-2-yl-2~{H}-indazole, ... (4 entities in total)
Functional Keywords	fragment, complex, ythdc1, epitranscriptomic, rna binding protein
Biological source	Homo sapiens
Total number of polymer chains	2
Total formula weight	42602.86
Authors	Bedi, R.K.,Huang, D.,Sledz, P.,Caflisch, A. (deposition date: 2019-10-02, release date: 2020-03-04, Last modification date: 2024-01-24)
Primary citation	Bedi, R.K.,Huang, D.,Wiedmer, L.,Li, Y.,Dolbois, A.,Wojdyla, J.A.,Sharpe, M.E.,Caflisch, A.,Sledz, P. Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments. Acs Chem.Biol., 15:618-625, 2020 Cited by PubMed: 32101404 DOI: 10.1021/acschembio.9b00894 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation