6SRF

Crystal Structure of Human Prolidase G278N variant expressed in the presence of chaperones

Summary for 6SRF

• Entry DOI: 10.2210/pdb6srf/pdb
• Descriptor: Xaa-Pro dipeptidase, MANGANESE (II) ION, SODIUM ION, ... (7 entities in total)
• Functional Keywords: dipeptidase, metallohydrolase, prolidase, pathological variants, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 109083.45

Authors

Wator, E.,Wilk, P. (deposition date: 2019-09-05, release date: 2020-07-15, Last modification date: 2024-01-24)

• Primary citation: Wator, E.,Rutkiewicz, M.,Weiss, M.S.,Wilk, P.; Co-expression with chaperones can affect protein 3D structure as exemplified by loss-of-function variants of human prolidase.; Febs Lett., 594:3045-3056, 2020; PubMed: 32598484; DOI: 10.1002/1873-3468.13877

Experimental method

X-RAY DIFFRACTION (1.847 Å)