6SRE

Crystal Structure of Human Prolidase S202F variant expressed in the presence of chaperones

Summary for 6SRE

Entry DOI	10.2210/pdb6sre/pdb
Descriptor	Xaa-Pro dipeptidase, MANGANESE (II) ION, GLYCEROL, ... (7 entities in total)
Functional Keywords	hydrolase, prolidase, metallopeptidase, pathological variant
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	109181.39
Authors	Wator, E.,Rutkiewicz, M.,Wilk, P. (deposition date: 2019-09-05, release date: 2020-07-15, Last modification date: 2024-01-24)
Primary citation	Wator, E.,Rutkiewicz, M.,Weiss, M.S.,Wilk, P. Co-expression with chaperones can affect protein 3D structure as exemplified by loss-of-function variants of human prolidase. Febs Lett., 594:3045-3056, 2020 Cited by PubMed: 32598484 DOI: 10.1002/1873-3468.13877 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.39 Å)

Structure validation