6SF0
Crystal Structure of Ancestral Flavin-containing monooxygenase (FMO) 2 in the presence of NADP+
Summary for 6SF0
Entry DOI | 10.2210/pdb6sf0/pdb |
Descriptor | Ancestral Flavin-containing monooxygenase (FMO) 2, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total) |
Functional Keywords | flavin, enzyme, membrane protein, ancestral sequence reconstruction, oxidoreductase |
Biological source | synthetic construct |
Total number of polymer chains | 4 |
Total formula weight | 251302.83 |
Authors | Nicoll, C.,Bailleul, G.,Fiorentini, F.,Mascotti, M.L.,Fraaije, M.,Mattevi, A. (deposition date: 2019-07-30, release date: 2019-12-25, Last modification date: 2024-01-24) |
Primary citation | Nicoll, C.R.,Bailleul, G.,Fiorentini, F.,Mascotti, M.L.,Fraaije, M.W.,Mattevi, A. Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs. Nat.Struct.Mol.Biol., 27:14-24, 2020 Cited by PubMed: 31873300DOI: 10.1038/s41594-019-0347-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.01 Å) |
Structure validation
Download full validation report