6SCX

Crystal structure of the catalytic domain of human NUDT12 in complex with 7-methyl-guanosine-5'-triphosphate

Summary for 6SCX

Entry DOI	10.2210/pdb6scx/pdb
Descriptor	Peroxisomal NADH pyrophosphatase NUDT12, CADMIUM ION, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
Functional Keywords	nudix protein, denadding enzyme, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	122628.90
Authors	McCarthy, A.A.,Chen, K.M.,Wu, H.,Li, L.,Homolka, D.,Gos, P.,Fleury-Olela, F.,Pillai, R.S. (deposition date: 2019-07-25, release date: 2020-01-08, Last modification date: 2024-01-24)
Primary citation	Wu, H.,Li, L.,Chen, K.M.,Homolka, D.,Gos, P.,Fleury-Olela, F.,McCarthy, A.A.,Pillai, R.S. Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs. Cell Rep, 29:4422-4434.e13, 2019 Cited by PubMed: 31875550 DOI: 10.1016/j.celrep.2019.11.108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.92 Å)

Structure validation