6SBH
Human Carbonic Anhydrase II in complex with 4-pentylbenzenesulfonamide.
Summary for 6SBH
| Entry DOI | 10.2210/pdb6sbh/pdb |
| Related | 6GDC 6GM9 6HQX 6HR3 6HXD 6I0W 6I1U 6I2F 6I3E 6RG5 |
| Descriptor | Carbonic anhydrase 2, ZINC ION, MERCURY (II) ION, ... (8 entities in total) |
| Functional Keywords | inhibitor, complex, co2 conversion, lyase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 31197.53 |
| Authors | Gloeckner, S.,Ngo, K.,Heine, A.,Klebe, G. (deposition date: 2019-07-20, release date: 2020-04-08, Last modification date: 2024-01-24) |
| Primary citation | Glockner, S.,Ngo, K.,Sager, C.P.,Hufner-Wulsdorf, T.,Heine, A.,Klebe, G. Conformational Changes in Alkyl Chains Determine the Thermodynamic and Kinetic Binding Profiles of Carbonic Anhydrase Inhibitors. Acs Chem.Biol., 15:675-685, 2020 Cited by PubMed: 32027480DOI: 10.1021/acschembio.9b00895 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (0.95 Å) |
Structure validation
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