6S24
Crystal structure of the TgGalNAc-T3 in complex with UDP, manganese and the peptide 3
Summary for 6S24
Entry DOI | 10.2210/pdb6s24/pdb |
Descriptor | Polypeptide N-acetylgalactosaminyltransferase, ALA-THR-GLY-ALA-GLY-ALA-GLY-ALA-GLY-THR-THR-PRO-GLY-PRO, TRIS(HYDROXYETHYL)AMINOMETHANE, ... (9 entities in total) |
Functional Keywords | galnac-ts, galnac-t3, long-range glycosylation preference, (glyco)peptides, molecular dynamics, specificity, enzyme kinetics, fgf23, phosphate homeostasis, transferase |
Biological source | Taeniopygia guttata (Zebra finch) More |
Total number of polymer chains | 2 |
Total formula weight | 76035.18 |
Authors | de las Rivas, M.,Daniel, E.J.P.,Narimatsu, Y.,Companon, I.,Kato, K.,Hermosilla, P.,Thureau, A.,Ceballos-Laita, L.,Coelho, H.,Bernado, P.,Marcelo, F.,Hansen, L.,Lostao, A.,Corzana, F.,Clausen, H.,Gerken, T.A.,Hurtado-Guerrero, R. (deposition date: 2019-06-20, release date: 2019-12-25, Last modification date: 2024-01-24) |
Primary citation | de Las Rivas, M.,Paul Daniel, E.J.,Narimatsu, Y.,Companon, I.,Kato, K.,Hermosilla, P.,Thureau, A.,Ceballos-Laita, L.,Coelho, H.,Bernado, P.,Marcelo, F.,Hansen, L.,Maeda, R.,Lostao, A.,Corzana, F.,Clausen, H.,Gerken, T.A.,Hurtado-Guerrero, R. Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3. Nat.Chem.Biol., 16:351-360, 2020 Cited by PubMed: 31932717DOI: 10.1038/s41589-019-0444-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.12 Å) |
Structure validation
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