6S0U

The crystal structure of kanamycin B dioxygenase (KanJ) from Streptomyces kanamyceticus in complex with nickel and 2-oxoglutarate

Summary for 6S0U

Entry DOI	10.2210/pdb6s0u/pdb
Descriptor	Kanamycin B dioxygenase, 2-OXOGLUTARIC ACID, NICKEL (II) ION, ... (7 entities in total)
Functional Keywords	non-heme iron dioxygenase, alpha-ketoglutarate dioxygenase, kanamycin biosynthesis, kanj, oxidoreductase, 2-oxoglutarate, metal binding protein
Biological source	Streptomyces kanamyceticus
Total number of polymer chains	6
Total formula weight	186767.18
Authors	Mrugala, B.,Porebski, P.J.,Niedzialkowska, E.,Minor, W.,Borowski, T. (deposition date: 2019-06-18, release date: 2020-07-08, Last modification date: 2024-01-24)
Primary citation	Mrugala, B.,Milaczewska, A.,Porebski, P.J.,Niedzialkowska, E.,Guzik, M.,Minor, W.,Borowski, T. A study on the structure, mechanism, and biochemistry of kanamycin B dioxygenase (KanJ)-an enzyme with a broad range of substrates. Febs J., 288:1366-1386, 2021 Cited by PubMed: 32592631 DOI: 10.1111/febs.15462 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation