6RME

Structure of IMP bound Plasmodium falciparum IMP-nucleotidase mutant D172N

Summary for 6RME

• Entry DOI: 10.2210/pdb6rme/pdb
• Related: 6RMD 6RMO 6RMW 6RN1 6RNH
• Descriptor: IMP-specific 5'-nucleotidase, putative, INOSINIC ACID, MAGNESIUM ION, ... (9 entities in total)
• Functional Keywords: nucleotidase, hydrolase, activator, complex, biosynthetic protein
• Biological source: Plasmodium falciparum (isolate 3D7); More
• Total number of polymer chains: 8
• Total formula weight: 365200.55

Authors

Carrique, L.,Ballut, L.,Violot, S.,Aghajari, N. (deposition date: 2019-05-06, release date: 2020-07-08, Last modification date: 2024-01-24)

• Primary citation: Carrique, L.,Ballut, L.,Shukla, A.,Varma, N.,Ravi, R.,Violot, S.,Srinivasan, B.,Ganeshappa, U.T.,Kulkarni, S.,Balaram, H.,Aghajari, N.; Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase.; Nat Commun, 11:3228-3228, 2020; PubMed: 32591529; DOI: 10.1038/s41467-020-17013-x

Experimental method

X-RAY DIFFRACTION (3.4 Å)