6RF2
Cryo-EM structure of the C-terminal DC repeat (CDC) of human doublecortin (DCX) bound to 13-protofilament GDP.Pi-microtubule
Summary for 6RF2
Entry DOI | 10.2210/pdb6rf2/pdb |
EMDB information | 4861 |
Descriptor | Tubulin alpha-1B chain, Tubulin beta-2B chain, Neuronal migration protein doublecortin, ... (7 entities in total) |
Functional Keywords | microtubule-associated protein, neuronal migration protein, microtubule nucleation and stabilisation, cytosolic protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 204825.26 |
Authors | Manka, S.W. (deposition date: 2019-04-12, release date: 2020-05-13, Last modification date: 2021-03-03) |
Primary citation | Manka, S.W.,Moores, C.A. Pseudo-repeats in doublecortin make distinct mechanistic contributions to microtubule regulation. Embo Rep., 21:e51534-e51534, 2020 Cited by PubMed: 33051979DOI: 10.15252/embr.202051534 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.2 Å) |
Structure validation
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