6RB3

Structural basis for recognition and ring-cleavage of the Pseudomonas quinolone signal (PQS) by AqdC variant in complex with its substrate

Summary for 6RB3

Entry DOI	10.2210/pdb6rb3/pdb
Descriptor	Putative dioxygenase (1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase), 2-heptylquinoline-3,4-diol (3 entities in total)
Functional Keywords	dioxygenase; alpha/beta hydrolase fold, catalytic triad, quorum sensing, pseudomonas quinolone signal, pseudomonas aeruginosa, hydrolase
Biological source	Mycobacterium abscessus
Total number of polymer chains	3
Total formula weight	90017.93
Authors	Wullich, S.,Kobus, S.,Smits, S.H.,Fetzner, S. (deposition date: 2019-04-09, release date: 2019-07-03, Last modification date: 2024-01-24)
Primary citation	Wullich, S.C.,Kobus, S.,Wienhold, M.,Hennecke, U.,Smits, S.H.J.,Fetzner, S. Structural basis for recognition and ring-cleavage of the Pseudomonas quinolone signal (PQS) by AqdC, a mycobacterial dioxygenase of the alpha / beta-hydrolase fold family. J.Struct.Biol., 207:287-294, 2019 Cited by PubMed: 31228546 DOI: 10.1016/j.jsb.2019.06.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation