6R6T
Crystal structure of mouse cis-aconitate decarboxylase
Summary for 6R6T
| Entry DOI | 10.2210/pdb6r6t/pdb |
| Descriptor | Cis-aconitate decarboxylase (2 entities in total) |
| Functional Keywords | immunity, inflammatory response, innate immunity, antimicrobial, decarboxylase, cis-aconitate, itaconate, lyase |
| Biological source | Mus musculus (Mouse) |
| Total number of polymer chains | 2 |
| Total formula weight | 115743.17 |
| Authors | Lukat, P.,Chen, F.,Saile, K.,Buessow, K.,Pessler, F.,Blankenfeldt, W. (deposition date: 2019-03-28, release date: 2019-09-25, Last modification date: 2024-01-24) |
| Primary citation | Chen, F.,Lukat, P.,Iqbal, A.A.,Saile, K.,Kaever, V.,van den Heuvel, J.,Blankenfeldt, W.,Bussow, K.,Pessler, F. Crystal structure ofcis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis. Proc.Natl.Acad.Sci.USA, 116:20644-20654, 2019 Cited by PubMed: 31548418DOI: 10.1073/pnas.1908770116 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.535 Å) |
Structure validation
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