6QXZ
Solution structure of the ASHH2 CW domain with the N-terminal histone H3 tail mimicking peptide monomethylated on lysine 4
Replaces: 6HBOSummary for 6QXZ
Entry DOI | 10.2210/pdb6qxz/pdb |
NMR Information | BMRB: 27251 |
Descriptor | Histone-lysine N-methyltransferase ASHH2, ALA-ARG-THR-MLZ-GLN-THR-ALA-ARG-TYR, ZINC ION (3 entities in total) |
Functional Keywords | the cw domain of the methyltransferase from arabidopsis (ashh2). ashh2 binds mono- di- and tri-methylated on k4 n-terminal histone tail h3 via cw domain., plant protein, transferase |
Biological source | Arabidopsis thaliana (thale cress) More |
Total number of polymer chains | 2 |
Total formula weight | 10067.35 |
Authors | Dobrovolska, O.,Madeleine, N.,Teigen, K.,Halskau, O.,Bril'kov, M. (deposition date: 2019-03-08, release date: 2019-12-04, Last modification date: 2023-06-14) |
Primary citation | Dobrovolska, O.,Brilkov, M.,Madeleine, N.,Odegard-Fougner, O.,Stromland, O.,Martin, S.R.,De Marco, V.,Christodoulou, E.,Teigen, K.,Isaksson, J.,Underhaug, J.,Reuter, N.,Aalen, R.B.,Aasland, R.,Halskau, O. The Arabidopsis (ASHH2) CW domain binds monomethylated K4 of the histone H3 tail through conformational selection. Febs J., 287:4458-4480, 2020 Cited by PubMed: 32083791DOI: 10.1111/febs.15256 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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