6Q6C

Pore-modulating toxins exploit inherent slow inactivation to block K+ channels

Summary for 6Q6C

Entry DOI	10.2210/pdb6q6c/pdb
Descriptor	Kunitz-type conkunitzin-S1, PHOSPHATE ION, NITRATE ION, ... (5 entities in total)
Functional Keywords	toxin
Biological source	Conus striatus (Striated cone)
Total number of polymer chains	2
Total formula weight	14571.35
Authors	Karbat, I.,Gueta, H.,Fine, S.,Szanto, T.,Hamer-Rogotner, S.,Dym, O.,Frolow, F.,Gordon, D.,Panyi, G.,Gurevitz, M.,Reuveny, E. (deposition date: 2018-12-10, release date: 2019-08-21, Last modification date: 2024-01-24)
Primary citation	Karbat, I.,Altman-Gueta, H.,Fine, S.,Szanto, T.,Hamer-Rogotner, S.,Dym, O.,Frolow, F.,Gordon, D.,Panyi, G.,Gurevitz, M.,Reuveny, E. Pore-modulating toxins exploit inherent slow inactivation to block K+channels. Proc.Natl.Acad.Sci.USA, 116:18700-18709, 2019 Cited by PubMed: 31444298 DOI: 10.1073/pnas.1908903116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation