6PDX

Crystal structure of C585 Fab in complex with influenza virus hemagglutinin from A/Switzerland/9715293/2013 (H3N2)

Summary for 6PDX

• Entry DOI: 10.2210/pdb6pdx/pdb
• Descriptor: Hemagglutinin, C585 Fab heavy chain, C585 Fab light chain, ... (6 entities in total)
• Functional Keywords: influenza virus, hemagglutinin, broadly neutralizing antibody, h3n2, viral protein, immune system
• Biological source: Influenza A virus; More
• Total number of polymer chains: 9
• Total formula weight: 324143.14

Authors

Qiu, Y.,Zhou, Y. (deposition date: 2019-06-19, release date: 2019-12-18, Last modification date: 2020-07-29)

• Primary citation: Qiu, Y.,Stegalkina, S.,Zhang, J.,Boudanova, E.,Park, A.,Zhou, Y.,Prabakaran, P.,Pougatcheva, S.,Ustyugova, I.V.,Vogel, T.U.,Mundle, S.T.,Oomen, R.,Delagrave, S.,Ross, T.M.,Kleanthous, H.,Qiu, H.; Mapping of a Novel H3-Specific Broadly Neutralizing Monoclonal Antibody Targeting the Hemagglutinin Globular Head Isolated from an Elite Influenza Virus-Immunized Donor Exhibiting Serological Breadth.; J.Virol., 94:-, 2020; PubMed: 31826999; DOI: 10.1128/JVI.01035-19

Experimental method

X-RAY DIFFRACTION (3.993 Å)