6PAX
CRYSTAL STRUCTURE OF THE HUMAN PAX-6 PAIRED DOMAIN-DNA COMPLEX REVEALS A GENERAL MODEL FOR PAX PROTEIN-DNA INTERACTIONS
Summary for 6PAX
Entry DOI | 10.2210/pdb6pax/pdb |
Descriptor | 26 NUCLEOTIDE DNA, HOMEOBOX PROTEIN PAX-6, ... (4 entities in total) |
Functional Keywords | pax, paired domain, transcription, protein-dna interactions, gene regulation-dna complex, gene regulation/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P26367 |
Total number of polymer chains | 3 |
Total formula weight | 30494.86 |
Authors | Xu, H.E.,Rould, M.A.,Xu, W.,Epstein, J.A.,Maas, R.L.,Pabo, C.O. (deposition date: 1999-04-22, release date: 1999-07-13, Last modification date: 2024-04-03) |
Primary citation | Xu, H.E.,Rould, M.A.,Xu, W.,Epstein, J.A.,Maas, R.L.,Pabo, C.O. Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding. Genes Dev., 13:1263-1275, 1999 Cited by PubMed: 10346815PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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