6OV3

Crystal structure of human claudin-9 in complex with Clostridium perfringens entertoxin C-terminal domain in open form

Summary for 6OV3

• Entry DOI: 10.2210/pdb6ov3/pdb
• Related: 6OV2
• Descriptor: Claudin-9, Heat-labile enterotoxin B chain (2 entities in total)
• Functional Keywords: claudin, enterotoxin, tight junction protein, transmembrane protein, cell adhesion
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 37657.77

Authors

Vecchio, A.J.,Stroud, R.M. (deposition date: 2019-05-06, release date: 2019-09-04, Last modification date: 2023-10-11)

• Primary citation: Vecchio, A.J.,Stroud, R.M.; Claudin-9 structures reveal mechanism for toxin-induced gut barrier breakdown.; Proc.Natl.Acad.Sci.USA, 116:17817-17824, 2019; PubMed: 31434788; DOI: 10.1073/pnas.1908929116

Experimental method

X-RAY DIFFRACTION (3.25 Å)