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6OMO

Human BMP6 homodimer

Summary for 6OMO
Entry DOI10.2210/pdb6omo/pdb
DescriptorBone morphogenetic protein 6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ISOPROPYL ALCOHOL, ... (6 entities in total)
Functional Keywordsbmp, bone morphogenetic protein, cytokine
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight24771.57
Authors
Juo, Z.S.,Seeherman, H. (deposition date: 2019-04-19, release date: 2019-05-08, Last modification date: 2020-07-29)
Primary citationSeeherman, H.J.,Berasi, S.P.,Brown, C.T.,Martinez, R.X.,Juo, Z.S.,Jelinsky, S.,Cain, M.J.,Grode, J.,Tumelty, K.E.,Bohner, M.,Grinberg, O.,Orr, N.,Shoseyov, O.,Eyckmans, J.,Chen, C.,Morales, P.R.,Wilson, C.G.,Vanderploeg, E.J.,Wozney, J.M.
A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix.
Sci Transl Med, 11:-, 2019
Cited by
PubMed: 31019025
DOI: 10.1126/scitranslmed.aar4953
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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